A toxoid is a bacterial toxin (usually an exotoxin) whose toxicity has been inactivated or suppressed either by chemical or heat treatment, while other properties, typically immunogenicity, are maintained.

A vaccine is a biological preparation that provides active acquired immunity to a particular disease.A vaccine typically contains an agent that resembles a disease-causing microorganism and is often made from weakened or killed forms of the microbe, its toxins, or one of its surface proteins.